The HER2-Positive Breast Cancer Landscape | CancerNetwork
cancernetwork.com
The HER2-Positive Breast Cancer Landscape | CancerNetwork
Joyce O’Shaughnessy, MD shares an overview of the HER2-positive breast cancer landscape, focusing on prognosis and risk of recurrence for patients with early-stage and metastatic breast cancer.
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Dose up on Instagram‎: "👇🏻👇🏻👇🏻 🎗️ سرطان الثدي الإيجابي لـ HER2 ودور Trastuzumab مريضة مشخصة بسرطان ثدي يتميّز بفرط تعبير HER2 (Human Epidermal Growth Factor Receptor 2)، وهو نمط يرتبط بسلوك عدواني ومعدل نكس أعلى في حال عدم المعالجة النوعية. في هذه الحالات، يُعد العلاج الموجّه حجر الأساس في الخطة العلاجية. 🔬 الآلية الجزيئية للمرض: مستقبل HER2 هو مستقبل تيروزين كيناز يشارك في تنظيم نمو الخلايا وانقسامها. فرط التعبير عن HER2 يؤدي إلى تنشيط دائم لمسارات التكاثر الخلوي وزيادة خباثة الورم. 💉
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Dose up on Instagram‎: "👇🏻👇🏻👇🏻 🎗️ سرطان الثدي الإيجابي لـ HER2 ودور Trastuzumab مريضة مشخصة بسرطان ثدي يتميّز بفرط تعبير HER2 (Human Epidermal Growth Factor Receptor 2)، وهو نمط يرتبط بسلوك عدواني ومعدل نكس أعلى في حال عدم المعالجة النوعية. في هذه الحالات، يُعد العلاج الموجّه حجر الأساس في الخطة العلاجية. 🔬 الآلية الجزيئية للمرض: مستقبل HER2 هو مستقبل تيروزين كيناز يشارك في تنظيم نمو الخلايا وانقسامها. فرط التعبير عن HER2 يؤدي إلى تنشيط دائم لمسارات التكاثر الخلوي وزيادة خباثة الورم. 💉
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