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JuMed on Instagram: "Marfan Syndrome — more than just “being tall.” Marfan is a connective-tissue disorder caused by a mutation in the FBN1 (Fibrillin-1) gene. When fibrillin is faulty, the elastic fibers in your body weaken — and the effects hit multiple systems: 🦴 Skeletal: tall, long limbs, long fingers (arachnodactyly), chest wall deformities 👁️ Eyes: lens dislocation, early myopia ❤️ Heart & Aorta: aortic root dilation, aneurysm risk, mitral valve prolapse — the most serious complications
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Yun fong | NCLEX備考日記🍁 on Instagram: "🎯 主題: Marfan syndrome（瑪芬氏症候群） 🔍 Marfan syndrome is an autosomal dominant connective tissue disorder caused by mutations in the FBN1 gene, resulting in defective fibrillin-1 synthesis and weakened connective tissue that affects the skeletal, cardiovascular, and ocular systems. （瑪芬氏症為一種染色體顯性遺傳的結締組織疾病，由 FBN1 基因突變引起 fibrillin-1 合成缺陷，導致結締組織脆弱，進而影響骨骼、心血管與眼部系統） 🚨臨床表現（Clinical manifestations） 🦴 Tall, thin body with long limbs a
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@theeyecareoptom on Instagram: "Marfan Syndrome Direction of lens : Superior and temporal (up and out). Zonules: Often intact but weakened. Onset: Can appear later in life (e.g., 4th-5th decade). Other: Normal intellect, aortic issues, no increased clotting risk. Homocystinuria Direction: Inferior and medial (down and in). Zonules: Often broken. Onset: Tends to be detected earlier in life, with more complete dislocations. Other: Intellectual disability, osteoporosis, high risk of blood clots (th
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