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0:58
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MedLecturesMadeEasy
Phases of clinical trials
Preclinical: Laboratory & animal models Goal: Explore if & how new treatment may work Phase I: Small number (eg, 20-100) of healthy subjects Goal: Evaluate toxicity, maximum tolerated dose, adverse effects, pharmacokinetics & pharmacodynamics of new treatment (safety) Phase II: Small number (eg, up to a few hundred) of affected subjects Goal ...
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Jul 28, 2023
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#medical
Recent studies show new antibody drugs can slow cognitive decline in people with early-onset Alzheimer’s — a critical finding for a disease with no cure. CBS News chief medical correspondent @DrLaPook visits Washington University School of Medicine in St. Louis, where researchers are testing treatments before symptoms appear. (The clinical trials involve the 1 to 2 percent of people with Alzheimer's who are genetically predisposed to developing dementia.) He also speaks with philanthropist @Bill
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Bill Gates, who has donated $300 million to support Alzheimer's research, tells CBS News chief medical correspondent Dr. Jon LaPook that he's "optimistic" about disease prevention. Recent studies have shown new antibody drugs to slow cognitive decline among people with early-onset Alzheimer's — a critical finding, given that the disease, as of now, has no cure. Dr. LaPook has more this Sunday. https://cbsn.ws/4oXQkFa | CBS Sunday Morning
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