Israel hit more targets in Tehran and Iranian missiles fired at Israel killed at least 14, as the conflict entered a third day

Israel and Iran have opened a new chapter in their long history of conflict when Israel launched a major attack with strikes early Friday on Tehran.

Regime change in Iran could be a result of Israel's military attacks on the country, Israeli Prime Minister Benjamin Netanyahu told Fox News on Sunday, saying Israel would do whatever is necessary to remove the "existential threat" posed by Tehran.

DUBAI, United Arab Emirates (AP) — Israel launched an expanded assault on Iran on Sunday, with direct strikes targeting its energy industry and Defense Ministry headquarters, while Tehran unleashed a fresh barrage of missiles blamed for the deaths of four people and injuries of many others.

Iran and Israel have launched more round of missiles at each other as the Middle East conflict escalates. Follow our live updates.

Israel targeted Iran’s Defense Ministry headquarters in Tehran and sites it alleged were associated with Iran’s nuclear program, while Iranian missiles evaded Israeli air defenses and slammed into buildings deep inside Israel.

Iran conflict could open opportunities for Russia to possibly become a power broker to help end the confrontation.

Israel launched a wave of unprecedented strikes on Iran shortly before sunrise Friday morning, hitting key sites in the nation’s nuclear program.