2006), as discussed later in this article. Chromatin structure is highly complex and impressively dynamic. Scientists now realize that the nucleosome, which was once thought to be static ...

Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct structures of the chromatin remodeler SNF2H offering a comprehensive view the ...

As previously mentioned, chromatin is remodeled (and thus, nucleosome structure is altered) primarily through posttranslational modifications of histone proteins, which actually change the ...

This discovery changes how scientists think about chromatin. Instead of being a static structure, chromatin is constantly moving, influencing how genes are read and used by the cell. "In simple ...

Scientists at St. Jude Children’s Research Hospital used a series of cryo-EM structures to visualize dynamics pivotal to chromatin remodeling, a process implicated in cancer and developmental ...