Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions. The DNA blueprint is carefully read, transcribed, and ...

To summarize, three initiation inhibitors sharing overlapping binding sites on the ribosome perform differently ... its mild inhibiting effect could be associated with mRNA sequence used in the study.

Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, 635 Barnhill, Indianapolis, Indiana46202-3082, United States ...

coli strain has only one rRNA sequence — a number reduced ... enabled the authors to identify binding sites for LAR on the ribosome. The authors report that LAR inhibits a protein-synthesis ...

INSERM U964, CNRS UMR7104, Université de Strasbourg, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), 67404 Illkirch, France ...

These proteins insert into the inner membrane co-translationally. Therefore, mitochondrial ribosomes engage with the OXA1L-insertase and membrane-associated proteins, which support membrane insertion ...

We identify genes connected to mitochondrial function and ribosome biogenesis as direct MYC/HCF-1 targets ... VIC domain of HCF-1 and an atypical HBM within MbIV that carries the sequence 'QHNY' ...

A far from exhaustive list of genomic patterns includes (i) tandem repeats and transposable elements, (ii) stretches of GC- or AT-rich sequences (e.g., CpG islands in mammalian genomes), (iii) binding ...

A growing number of cellular mRNAs are thought to possess internal ribosome entry sites (IRESs), sequences that permit translation of a transcript independent of its 5′ end and cap structure. Although ...