Researchers have successfully employed an algorithm to identify potential mutations which increase disease risk in the noncoding regions our DNA, which make up the vast majority of the human genome.

Researchers from Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of ...

A seminal study has uncovered a new genetic cause of neurodevelopmental disorders (NDDs). The discovery offers both closure and hope to potentially thousands of families worldwide who have long been ...

University of Delaware's Mona Batish is a molecular biologist. She studies circular RNAs formed as a result of so-called ...

Researchers have identified mutations in the non-coding gene RNU2-2 as a cause of a newly defined neurodevelopmental disorder ...

Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA ...

Much of the "junk" DNA in Drosophila shows signs of either negative or positive selection, according to a study in this week's Nature. An analysis by Peter Andolfatto of the University of California, ...

RNA-based therapeutics are gaining traction due ... down the field of targets from tens of thousands (76-96% of the human genome), to just a few dozen viable treatment areas.

2015). MicroRNAs are small non-coding RNAs, approximately 21–25 nucleotides long, that regulate gene expression by inhibiting degradation or translation of target mRNAs. Transcribed by RNA polymerase ...

Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States ...

yet much of the non-coding genome is transcribed into RNA. Over the past few decades, scientists have discovered that these non-coding RNAs mediate essential functions in healthy cells — and ...