Nature uses a common framework when building organisms as different as yeast, worms, fruit flies, mice, and humans. This makes it possible for scientists to learn about how our own genes work by ...

A recent study highlights how DNA microarray technology enables high-throughput gene analysis, supporting variation detection, expression profiling, and clinical research. By refining probe design and ...

The enormous potential of miRNAs is driving new technologies for research, diagnostic, and therapeutic applications. miRNAs, a class of small noncoding RNAs of 19–30 nucleotides in length, regulate ...

Reading the fluorescent signals on microarrays that give a glimpse into cellular gene expression is typically the job of laser scanners. This technology works well, but lasers can be very cumbersome ...

When it comes to enzymes, protein abundance does not necessarily translate into protein activity: Post-translational modifications such as phosphorylation can dramatically alter enzyme function.