Mapping gene disruptions in sporadic early onset Alzheimer's disease across key brain regions

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to ...

How major nuclear protein complexes control specialized gene regulation in cancer and beyond

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

An AI-driven strategy to accelerate microbial gene function discovery

We know the genes, but not their functions—to resolve this long-standing bottleneck in microbial research, a joint research ...
eLife

Nonlinear transcriptional responses to gradual modulation of transcription factor dosage

A new CRISPR-based approach for tuning gene expression up and down allowed identification of how other genes' expression responds to changes of transcription factors.
AlphaGalileo

SIK1: A PROTECTIVE REGULATOR IN EV-D68–INDUCED ASTHMA

New Study Shows SIK1 Strengthens Antiviral Immunity to Limit EV-D68–Induced Asthma Exacerbations Asthma is a chronic ...

Researchers expand human genome map to 2.37 million regulatory DNA elements

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...