Arcus will now refocus its efforts outside of TIGIT, specifically on its asset casdatifan, an HIF-2a inhibitor once backed by Gilead, as well as its earlier stage small-molecule inflammatory and ...
Non-opioid analgesic shows efficacy in several animal pain models, including diabetic and chemotherapy-induced neuropathic ...
Non-opioid analgesic shows efficacy in several animal pain models, including diabetic and chemotherapy-induced neuropathic pain Compelling safety and pharmacokinetic profiles in animals support IND-en ...
HanchorBio Announces Oral Presentation of HCB101 at the ESMO Immuno-Oncology Congress 2025 ...
Discusses Year-End Late-Stage Pipeline Review With Focus on Clinical and Regulatory Developments December 16, 2025 11:15 AM ...
1don MSN
Cracking the code of a hidden cancer receptor: How scientists found the first true Frizzled blocker
Researchers at Karolinska Institutet have identified small molecules capable of influencing a hard-to-target receptor family ...
One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack ...
A hidden “jack-in-the-box” mechanism inside T cells may hold the key to unlocking more powerful cancer immunotherapies.
News-Medical.Net on MSN
Cryo-EM reveals NPFFR1 activation and guides novel ligand design
This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of ...
News-Medical.Net on MSN
Novel cryo-EM findings could revolutionize T cell immunotherapy design
One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack ...
Neurocrine Biosciences, Inc. ( NBIX) Discusses Progress and Strategy in Neurology and Obesity R&D Programs December 16, 2025 12:00 PM EST ...
African Swine Fever Virus, ASFV, Viral Entry, Host Cell Invasion, CD163, Siglec-1, Macropinocytosis, Endosomal Escape, Immune Evasion, Signaling Pathways Share and Cite: Marcelino, K.B. and Fang, G.J.
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