Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a ...

Scientists could reshape cancer treatment by helping powerful drugs work better in the body by exploiting a surface protein called CD36 that helps pull substances into cells. This dramatically ...

In this interview, Technology Networks spoke with Dr. Lena Jonsson, product strategy manager at Cytiva, to explore the ...

OXFORD, UK I April 9, 2025 I Infinitopes Ltd today announces that the UK Medicines and Healthcare products Regulatory Agency (MHRA) has granted Clinical Trial ...

Drug discovery efforts have expanded beyond the traditional approaches of small molecules and antibodies to include cells.

1986, 1995, Ninomiya et al. 1990, Unander et al. 1995). Additionally, antitumour activity against sarcoma 180 ascites, leukemia in mice, and cytotoxic activity against certain cancer cell lines has ...

The presence of preformed cytotoxic antibodies against the donor ... positive (those reacting with 20 per cent or more of cell samples of random persons); negative (those reacting with less ...

Credit: Juan Gaertner via Shutterstock. Chimeric antigen receptor (CAR) T cell therapies have made remarkable strides in treating high-risk B-cell malignancies since the first CAR-T, Novartis’s ...

UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, United States Department of Medicine, University of California, San Francisco, ...

In response to infections, naive CD8 T cells give rise to effector and memory T cells. However, eliciting long-lived memory CD8 T cells remains a challenge for many infections. DNA demethylation of ...

That’s around 15,000 more misdemeanor arrests that prosecutors didn’t even charge. Indeed, under discovery reform an average of 65% of misdemeanors are either dismissed or declined ...