Most cells in the human body each contain about six feet of DNA. Yet the nucleus, where DNA is coiled, is no larger than a ...

April 3, 2025) Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this ...

Scientists at St. Jude Children’s Research Hospital used a series of cryo-EM structures to visualize dynamics pivotal to chromatin remodeling, a process implicated in cancer and developmental ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact ...

Using single-cell technologies, the researchers simultaneously analyzed ... Histone modifications alter the structure of chromatin, affecting how tightly the DNA is packaged and influence gene ...

Kanazawa University and colleagues have achieved a breakthrough in understanding sperm DNA packaging. Using high-speed atomic ...

Northwestern Medicine scientists have uncovered new details about the genetic structure of ... Inside cells, DNA mixes with proteins to form chromatin within the nucleus. Within chromatin ...

Now, for the first time, EMBL scientists have directly observed this process in high resolution under the microscope using a new chromatin ... cells. In fact, mutations in condensin structure ...