Histone tails and their epigenetic modifications play crucial roles in gene expression regulation by altering the architecture of chromatin. However, the structural mechanisms by which histone tails ...

Chromatin is a flexibly joined chain of nucleosomes that exists inside the nucleus of eukaryotic cells and has been described as a 'bead on a string'. Chromatin organization strengthens DNA for ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, determines which genetic instructions are activated. When this fails, the wrong ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...

Scientists have identified two proteins involved in regulating chromatin remodelling which could be promising therapeutic ...

Cold sore-causing HSV-1 doesn't just hijack cells it reconfigures the entire architecture of our DNA to aid its invasion.

Nucleus compression is likely to have a more global effect on chromatin than on specific gene expression, as shown in animal systems (5, 6, 22, 23). Furthermore, changes in global chromatin state have ...

Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the ...

There is more movement in our genome than we think. Almost half of the human genome consists of transposons—short DNA ...

We identified retinal projections to the perihabenular nucleus (pHb), a crucial area in LAN-induced negative mood, and demonstrated that the pHb continues to innervate the nucleus accumbens (NAc) in ...