Recently, p73, a new member of the p53 family, has been cloned and mapped to chromosome 1p36, a region that is frequently deleted in a variety of human cancers. p73 can activate p53-responsive ...

The precise mechanisms whereby anti-angiogenesis therapy blocks tumour growth or causes vascular toxicity are unknown. This article proposes that endothelial cells establish a vascular niche that ...

In endothelial cells treated with participants’ sera, vascular endothelial growth factor-stimulated nitric oxide levels were significantly lower for the marijuana smoker vs the nonuser group ...

The peripheral vascular devices industry is driven by the shift to drug-eluting stents and drug-coated balloons. Key trends include investments in bioresorbable scaffolds. Focus regions: North America ...

Fibroblast growth factor receptors (FGFRs; FGFR1, FGFR2, FGFR3, FGFR4) are frequently mutated oncogenes in solid cancers. The oncogenic potential of FGFR rearrangements and few hotspot point mutations ...

Background: Vepdegestrant, an oral PROTAC (PROteolysis TArgeting Chimera) ER degrader, showed encouraging clinical activity and was well tolerated in a phase 1/2 study in pretreated patients (pts) ...

Slevin et al 1 reported on elevated serum levels of vascular endothelial growth factor (VEGF) in patients with acute ischemic stroke. They claim to demonstrate a relationship between stroke volume and ...

1. Property Location Why It's Important The adage "location, location, location" is still king and continues to be the most important factor for profitability in real estate investing.

Chancellor Rachel Reeves unveils how the government plans to spend money in the coming years.

Furthermore, hypoxia is a powerful stimulus for angiogenesis, mediated by HIF-1α (hypoxia-inducible factor 1α), which promotes the release of VEGF (vascular endothelial growth factor) to stimulate ...