An experimental drug now in clinical trials as a cancer treatment could help boost the power of first-line tuberculosis (TB) ...

Scientists have found a surprising new way to make certain cancer drugs work dramatically better – by helping them get inside ...

Drugs and other treatments can be quite ... Working in a mouse model of triple-negative breast cancer, the researchers used their approach to slow tumor growth far more than treatment with ...

Brain Tumor Organoids Accurately Model Patient Response to CAR T Cell ... identified through a screen for genetic ... Repurposing Drug Shows Promise in Fighting Aggressive Brain Tumors Oct ...

Telomir-1 reduced tumor size by 50% in a prostate cancer model and protected against chemotherapy ... tumor development…We are seeing a drug that extends cellular health while simultaneously ...

These effects ultimately lead to improved efficacy in treating solid tumors ... The drug screening platform can assess FDA-approved small molecules using the CAR-T cell exhaustion model.

Contrary to concerns that telomere-elongating drugs may promote cancer, Telomir-1 demonstrated the opposite effect—actively suppressing tumor development, while selectively benefiting healthy cells.

City of Hope researchers demonstrate proof of concept for a novel targeted therapy for pancreatic cancer, exploiting transcription-replication conflicts to combat treatment resistance.