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A multi-omics approach was employed, including bulk RNA-seq analysis, methylation profiling, single-cell analysis, and spatial transcriptomics. Experimental methods included RT-qPCR, siRNA ...
Spatial transcriptomics analysis uncovered heterogeneous expression ... Additionally, the PRDX1-targeting siRNA and its corresponding negative control (Si-NC) were provided by RiboBio, based in ...
Transcriptomics is the study of the transcriptome—the complete set of RNA transcripts that are produced by the genome, under specific circumstances or in a specific cell—using high-throughput ...
Advancing single-cell research requires precise and reproducible tissue dissociation techniques. Manual methods can introduce variability, compromise cell viability and hinder downstream applications.
Loss function of tumor suppressor FRMD8 confers resistance to tamoxifen therapy via a dual mechanism
(A) Lysates of HEK293T cells co-transfected with Flag-ERα and FRMD8 siRNA as indicated were immunoblotted. (B-C) Lysates from T47D cells transiently transfected with control or FRMD8 siRNA were ...
We are pleased to introduce the EMBO reports Advisory Editorial Board. Members of the Board provide scientific advice to the editors for which we are very grateful. Should you wish to contact a Board ...
Correspondence to Dr Sang Geon Kim, College of Pharmacy, Seoul National University, Sillim-dong, Kwanak-gu, Seoul 151-742, South Korea; sgk{at}snu.ac.kr Objective Endoplasmic reticulum (ER) stress is ...
Postal address: H7 Medicin, Huddinge, H7 GUT Daub, 171 77 Stockholm ...
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