Vasculitis-specific molecules were screened using serum proteome analysis and whole-blood RNA sequencing, then validated with immunohistochemical staining and spatial transcriptome analysis. The ...

This collection of recent reviews and research articles published in Molecular Systems Biology highlights the use of diverse ‘omics’ technologies in systems biology. In the featured studies, data ...

The purpose of this study is to develop a classifier capable of accurately predicting the high-risk OS subtype using transcriptome and methylation data. Using the XGBoost algorithm, we developed a ...

Chair of Proteomics and Bioanalytics, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany Chair of Proteomics and Bioanalytics, School of Life Sciences, Technical ...

School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, 2 Xuelin Road, Qixia District, Nanjing 210023, People’s Republic of China School of Food Science and Pharmaceutical ...

For example, a researcher might perform a multiomics workflow to compare the genome, epigenome, transcriptome, and proteome of a muscle tissue sample from a patient with muscular dystrophy. To do so, ...

For instance, scientists used high throughput sequencing technologies for The Cancer Genome Atlas (TCGA) project–a massively successful NGS-based research effort to thoroughly characterize the genome, ...

Our findings indicate that the classical complement pathway is central for newborn immunity and our approach to characterize the plasma proteome in parallel with the transcriptome will provide crucial ...

The resulting data established the large-scale database for NFPA proteome, and provided the scientific data ... It also means that these 1088 DEGs at the level of transcriptome, through ...

We find that cells produce excess ribosomal proteins, amounting to a constant ≈8% of the proteome. Accordingly, ≈25% of ribosomal proteins expressed in rapidly growing cells does not contribute to ...