Furthermore, using a graph neural network approach ... radiation significantly alters the 3D genome structure, leading to distinct changes in chromatin interactions and gene regulation.

present a computational systems approach to elucidate the regulatory logic of the gene network for primed ... identify a distinct chromatin structure at clustered GBP innate immune genes that ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

This discovery changes how scientists think about chromatin. Instead of being a static structure, chromatin is constantly moving, influencing how genes are read and used by the cell. "In simple ...

Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct ...

Could a gene regulatory network in gut microbes have evolved its elaborate and tightly regulated molecular machinery only to pump out antibiotics indiscriminately? Researchers from the Institute of ...

In the default model, the graph representing each individual enhancer can be arbitrarily complicated. To show how the ABC Score formula can arise from the default model, we need to impose the further ...