Machine learning model predicts protein binding on gold nanoclusters

Researchers in the Nanoscience Center at the University of Jyväskylä, Finland, have developed a pioneering computational ...
EurekAlert!

Expanding the sequence spaces of synthetic binding protein using deep learning-based framework ProteinMPNN

Protein design is crucial for the treatment of human diseases, but traditional protein design methods have some limitations. Site-directed mutagenesis is highly dependent on the physiological ...
IEEE

Deep Learning-Based Crack Detection in Spiral-Welded Pipelines: A Novel Adaptive Convolutional Feature Extraction Method

Abstract: This article proposes a new time-series signal processing model for crack detection and localization in spiral-welded pipelines. Using the time-series signal of pipeline cracks as the ...
C&EN

Persistent Directed Flag Laplacian (PDFL)-Based Machine Learning for Protein–Ligand Binding Affinity Prediction

Department of Mathematics, Michigan State University, East Lansing, Michigan 48824, United States Department of Mathematics, Michigan State University, East Lansing, Michigan 48824, United States ...
eLife

An Integrated Machine Learning Approach Delineates an Entropic Expansion Mechanism for the Binding of a Small Molecule to α-Synuclein

This study describes the application of machine learning and Markov state models to characterize the binding mechanism of alpha-Synuclein to the small molecule Fasudil. The results suggest that ...
everydayfamilycooking

How to Cook a Spiral Ham

I just had to share my go-to recipe on how to cook a spiral ham because it’s a staple in my house each year. My recipe features a classic, old-fashioned pineapple brown sugar glaze that highlights the ...
洗護用品和肥皂

10 years on: A call to concrete action for a powerful legally binding instrument - 2024 Webinar series

This year marks the 10-year anniversary of the adoption of the Human Rights Council resolution that created the Intergovernmental Working Group (IGWG) on a legally binding instrument on business and ...
Common Sense Media

Binding 13: Boys of Tommen, Book 1

Parents need to know that Binding 13 is the first book in the bestselling Boys of Tommen series by Irish author Chloe Walsh. When Shannon and Johnny meet, their mutual attraction is undeniable, but ...
GitHub

UniSite: The First Cross-Structure Dataset and Learning Framework for End-to-End Ligand Binding Site Detection

The official implementation for "UniSite: The First Cross-Structure Dataset and Learning Framework for End-to-End Ligand Binding Site Detection". The detection of ligand binding sites for proteins is ...
IEEE

Inquiry into the services for bilingual learning needs of university students

Abstract: The service needs of bilingual learning of university students, is to use the concepts of services of scientific, to help the students understand and make the total planning and arrangement ...