coli strain has only one rRNA sequence — a number reduced ... enabled the authors to identify binding sites for LAR on the ribosome. The authors report that LAR inhibits a protein-synthesis ...

By combining these sequences into a flipbook ... proteins and the spring-like transitions of tRNA between ribosome-binding sites, which had not been previously seen in cells and could reveal ...

That mRNA is read and translated at a cell's ribosome ... initiation site, located downstream of a core promoter region and typically around a TATA box—a DNA sequence rich in thymine and adenine ...

To summarize, three initiation inhibitors sharing overlapping binding sites on the ribosome perform differently ... its mild inhibiting effect could be associated with mRNA sequence used in the study.

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions. The DNA blueprint is carefully read, transcribed, and ...

Researchers have successfully employed an algorithm to identify potential mutations which increase disease risk in the noncoding regions our DNA, which make up the vast majority of the human genome.

Another company looking to initiate clinical trials with an epigenetic-editor-based treatment for hepatitis is nChroma Bio.

A study by researchers at Fred Hutch Cancer Center published in Nature revises the standard story about transcription factors ...

"The main issue with understanding these interactions is that there is a competition between an ion binding to a certain receptor and that same ion wanting to be surrounded by solvent molecules ...

Because chemogenetic control relies on DREADD expression levels, understanding and quantifying the temporal dynamics of their expression is crucial for planning long-term experiments in monkeys. In ...

Research into transcription factors deepen understanding of the 'language' of the genome, offering insights into human development.