Mycobacteria are the world's most deadly bacteria --c ausing infectious diseases including tuberculosis (TB), which alone kills more than one million people each year. New drugs to fight these ...

Because RNAs are so central to our biology, they are also drivers of a wide array of diseases. Defects in how RNA is produced ...

Discover how a structural breakthrough in the chikungunya virus is opening new avenues for antiviral drug development and ...

An artistic depiction of a jumbo phage infecting a bacterium, with the EPI vesicle (circle) shown protecting the phage DNA ...

Catching HBV early can make a world of difference. Medical professionals typically use blood tests that check for signs of the virus in the body, such as HBV antigens or antibodies. They also ...

Six years before the start of the COVID-19 pandemic, an Ebola outbreak in West Africa had people fearing the possibility of a global outbreak. This was the first time many had ever heard of the virus, ...

These vaccines helped beat back the virus and showed that mRNA was safe ... is the speed at which they can be designed and synthesized. Once the chemical structure of the RNA and the means of delivery ...

A major challenge lies in the virus's structure and regulatory mechanisms ... Both are essential for nucleocapsid assembly, the regulation of RNA synthesis, and intracellular transport.

SINGAPORE – A new programme has been launched in Singapore to formally study the applications of ribonucleic acid (RNA) in vaccine development, as well as in disease therapy and prevention ...

As with proteins, determining RNA structure typically requires costly and time-consuming experimental methods. Computational tools can help, but RNA is a tougher nut to crack. One simple reason ...

Amplicons for amp R are shown in red, pAAV-ZsGreen1 backbone unique in green, E4 in blue, and rep in yellow. rAAV, recombinant adeno-associated virus. Credit: Human Gene Therapy (2025). DOI: 10. ...