Results described in the paper more generally suggest that the molecular mechanism of programmed cell death has been conserved evolutionarily from worms to mammals. "Concerning evolutionary ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological ...

A phase 3 clinical trial has shown that adding a targeted immunotherapy drug to chemotherapy dramatically improved – almost ...

The trial is anticipated to enrol 462 subjects and aims to confirm the safety and efficacy of the combination.

After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do ...

The surprising paradigm shift could lead to much more protective sunscreens and effective skin treatments.

The study is based on the analysis of human senescent cells in a specific tumor model — melanoma, which affects skin cells known as melanocytes — and, more specifically, melanocytes exposed to ...

A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over ...

The addition of sintilimab to neoadjuvant chemoradiotherapy achieved a 60% pathological complete response rate vs 47.3% with ...