Two types of RNA in our cell: Coding RNA directs cells to make proteins; Non-coding RNA performs a wide range of activities including gene regulation and maintaining chromosome structure.

Indeed, advances in technology have revealed that much of the noncoding genome gives rise to lncRNAs and other RNA molecules that affect all manner of cellular processes. “The vast majority of the ...

Regions of DNA that do not code for proteins may also be considered genes if they produce noncoding RNA with biological functions. Protein-coding versus noncoding genes When deciding the number of ...

Researchers have successfully employed an algorithm to identify potential mutations which increase disease risk in the noncoding regions our DNA, which make up the vast majority of the human genome.

The involvement of noncoding mRNAs in many regulatory ... has led to the hypothesis that an "RNA world" may have preceded the evolution of DNA and proteins (Gilbert, 1986). Small interfering ...

The research team found that a specific muscle protein, known as MEF2C, is significantly reduced in muscle cells with CP.

It is the first big biopharma group to tap into Haya's platform, which identifies genes coding for long non-coding RNA (lncRNA), a group that makes up a large proportion of the genome. That is a ...

A seminal study has uncovered a new genetic cause of neurodevelopmental disorders (NDDs). The discovery offers both closure and hope to potentially thousands of families worldwide who have long been ...

Three unrelated children with deletions of CHASERR, a long non-coding RNA, had a severe neurological ... they did a follow-up genome -- not just looking at the exome, but the overwhelming majority ...

Importantly, well over half of the human genome is devoted to producing ... The MUSC researchers focused on long non-coding enhancer RNA (Inc-eRNA), a specific type of lncRNA that interacts ...

RNA is similar to DNA but contains uracil instead of thymine (T ... Other ribozymes include self-splicing introns and the RNA component of the enzyme telomerase. Non-coding RNA molecules, such as ...

Researchers from Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of ...