Scientists develop a smarter mRNA therapy that knows which cells to target

Researchers at the Icahn School of Medicine at Mount Sinai have developed a first-of-its-kind mRNA system that switches on therapeutic genes preferentially inside targeted cells—an advance ...
Healio

FDA approves monthly PCSK9 inhibitor for high cholesterol

The FDA has approved lerodalcibep-liga, a third-generation injectable PCSK9 inhibitor, to reduce LDL cholesterol in adults ...
The American Journal of Managed Care

FDA Approves Once-Monthly PCSK9 Injection for LDL-C Reduction

Lerodalcibep-liga, a once-monthly PCSK9 inhibitor, significantly reduces LDL-C in hypercholesterolemia, including HeFH, with ...
News-Medical.Net

Injectable scaffold vaccine shows strong protection against implant-related MRSA

Research reveals that silica scaffolds can train the immune system against S. aureus, offering a novel approach to prevent ...
Frontiers

Multiple tail vein injections of adipose-derived mesenchymal stem cells ameliorate allergic rhinitis in mice: superior efficacy of prolonged regimens

Background: Adipose derived mesenchymal stem cells (ADSCs) are a subset of mesenchymal stem cells (MSCs), showing broad anti allergic effects in type 2 inflammation. Their systemic efficacy in ...
Frontiers

Immunization with the M12-N, M12-C, and M12-N+C fusion peptides derived from the M12 protein elicited varying levels of protective immune responses against multiple serotypes ...

The M protein located on the surface of group A Streptococcus has been extensively researched as a promising vaccine candidate. However, issues such as potential cross-reactivity with human tissues ...
urologytimes

European Commission approves subcutaneous pembrolizumab

The subcutaneous formulation of pembrolizumab is approved for all adult indications in Europe, offering faster administration than the intravenous version. Phase 3 trial results showed noninferior ...