Cell cycle-related kinase (CCRK) is essential for AR-induced hepatocarcinogenesis ... subsequently, expression of HBx. The viral transactivator in turn induced CCRK expression through enhanced AR ...

Whilst the ultimate outcome of the lytic cycle is production of new phage progeny and death ... eliminating susceptible hosts and promoting the propagation of resistance, by gene transfer for example, ...

Figure 3. The lytic replication cycle of herpesviruses. (1) Entry into the cell (steps ①, ②), (2) transfer of the capsid to the nucleus (steps③–⑤), (3) viral DNA replication and transcription (steps ⑥ ...

Here, we uncover a critical physiological role for a widely misunderstood class of autolytic enzymes, lytic transglycosylases (LTGs). We demonstrate that LTG activity is essential to survival by ...

We present a mathematical model of the ecological and evolutionary dynamics of such viral communication and show that a communication strategy in which phages use the lytic cycle early in an outbreak ...

The herpesvirus cycle is characterized by two distinct phases: latency and the productive or lytic cycle. During latency, no active viral production occurs and ... now been identified (Lee et al., ...