There are many things we’ve learned from studying the ancient Egyptians. One especially fascinating discovery was evidence of ...

By targeting a previously unexploited metabolic pathway essential for bacterial survival, the drug candidate may offer the potential to develop safer, shorter and more effective treatment regimens ...

Researchers reported in The New England Journal of Medicine that 4 months of rifampin was noninferior to 9 months of isoniazid for the treatment of adults with latent tuberculosis. The shorter ...

In this GEN webinar, Dave Lahr, PhD, Senior Director of Bioinformatics at Foghorn Therapeutics, discusses chromatin regulation and epigenetic mechanisms that shape transcriptional responses to ...

Immune checkpoint inhibitors provide durable clinical responses in multiple difficult-to-treat tumor types. The tumor microenvironment, tumor immunogenicity, antigen presentation, and classic ...

In contrast to the WHO recommendation to give all HIV- infected children over 12 months of age isoniazid preventive therapy, our results show no effect of isoniazid preventive therapy among this ...

Mechanism of action articles from across Nature Portfolio Mechanism of action describes the process by which a molecule, such as a drug, functions to produce a pharmacological effect.

TMC207 TMC207 (also known as R207910 or the 'J' compound) is a diarylquinoline that inhibits the proton pump of M. tuberculosis 's ATP synthase, a novel mechanism of action.

Exposed: Where Palestine Action plans to strike next Telegraph uncovers major recruitment drive days before group is proscribed as terrorist organisation ...

Indianapolis Vision Zero Task Force unveils draft Action Plan to reduce traffic fatalities to zero by 2035.

After two decades of fumbling, Warner Bros. abandons its live-action Akira dreams The classic anime's film rights will now be shopped to another studio, ideally one without solid pattern ...