According to the companies, an objective response rate of 54.8% was observed with Daiichi Sankyo and Merck's ifinatamab deruxtecan at a 12 mg/kg dose in pretreated patients. This dose has been ...

BASKING RIDGE, N.J. & RAHWAY, N.J.--(BUSINESS WIRE)--Results from an interim analysis of the dose-optimization part of the ongoing IDeate-Lung01 phase 2 trial showed ifinatamab deruxtecan (I-DXd ...

A trial-in-progress poster from the NSCLC cohort of a phase 1b trial evaluating the combination of datopotamab ... ICARUS-BREAST01 phase 2 study of patritumab deruxtecan (HER3-DXd) in patients ...

Six late-breaking presentations across lung and breast cancer trials of DXd ADCs, including two Presidential Symposia at WCLC featuring datopotamab deruxtecan data First ever clinical data from ...

The research team, led by UAB Department of Pathology Professor Upender Manne, Ph.D., conducted a series of experiments using colorectal cancer cell lines, patient-derived xenografts and mouse models ...

Daiichi Sankyo granted Merck exclusive, worldwide rights (excluding Japan) to co-develop and co-commercialize Daiichi's 3 antibody-drug conjugates (ADCs) including patritumab deruxtecan (HER3-DXd ...

Ribonucleotide reductase messenger 1 is a component of the nucleotide excision repair complex that is the predominant target of the nucleoside analogue gemcitabine. Overexpression of RRM1 has been ...

“He’s got that all-round combination of: he’s very fast, he’s big, he’s strong. He is very difficult to mark and he’s prolific,” Lineker, a prominent broadcaster with the BBC and ...

(RTTNews) - IO Biotech (IOBT) announced that the Independent Data Monitoring Committee found the data from the Pivotal Phase 3 Trial of IO102-IO103 in combination with KEYTRUDA (pembrolizumab ...

Shares of US protein-based vaccine developer Novavax (Nasdaq: NVAX) closed up 8.6% and added a further 1.8% to $12.60 in after-hours trading on Friday, on a positive development for its COVID-19 ...

Philadelphia is the home team, but they won’t be wearing green, choosing a fresh, new uniform combination they’ll wear for the first time. The Eagles have worn white jerseys and black pants ...