New research pioneered by The University of Western Australia is shedding light on the intricate dance between proteins, DNA ...

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and protects replicating DNA in dividing cells. This new structural and ...

In the pursuit of understanding the pathogenic expression mechanisms of bacteria and the advancements in biofoundry ...

Researchers from Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of ...

A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they ...

Prepare plasmid DNA using standard miniprep protocols ... Avoid fusions to the GFP fragments at the site of protein-protein interaction and consider optimizing the spacer length between the ...

The double ring, spool-like structure of RAD52 protects replicating DNA in dividing cells. A study led by the University of ...

A key protein network that keeps cells safe from the dangerous effects of transposable elements has been uncovered.

DNA strand displacement circuits are inching closer to becoming cellular machines. Scientists are finding ways to make these programmable nanodevices stable and functional inside living cells. If ...

Mutations fuel evolution while also causing diseases like cancer. Epigenome-targeted DNA repair can help organisms protect important genomic regions from mutation. However, the adaptive value, ...

leveraging the 3D structures of every human protein and all known interactions between proteins to decipher how mutations drive cancer. "DNA transcribes into RNA and then translates into proteins.

4 The term “cis” refers to interactions ... that mediate DNA repair and cell-cycle checkpoints, can also contribute to an unstable genome. A gene that encodes an RNA or protein that can ...