Single-cell multiomic analyses reveal known and new genes and pathways involved in the development of germ cells and provide a discovery platform for the scientific community.

The shape and mechanics of the nucleus are known to be influenced by internal factors, such as the organization of chromatin (the structure containing DNA) and the nuclear lamina (a network of ...

Despite this shortening, a half-foot of chromatin is still much too long to fit into the nucleus, which is typically only 10 to 20 microns in diameter. Therefore, chromatin is further coiled into ...

In addition to exporting materials out of the nucleus, the protein, called Exportin-1 (also called Xpo1 or Crm1), seems to play a role in promoting gene transcription, the process that creates RNA ...

The researchers next showed that when macrophages were exposed to inflammatory signals, their activity changed alongside ...

Hepatitis B virus infection remains one of the leading causes of liver disease, including cirrhosis and hepatocellular carcinoma.

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

Chronic hepatitis B virus (HBV) infection continues to pose a major global health threat. The virus evades immune responses and antiviral therapies due to the persistence of covalently closed circular ...