The common conception of DNA is in long, twisting strands, but in order to fit into the confines of the nucleus, DNA actually condenses into a strict structure called chromatin. Chromatin facilitates ...

New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

Inside the nucleus of a cell, the chromatin fiber interacts with itself to condense into a chromosome. The chromatin fiber also supports gene expression and replication of chromosomal DNA.

Harvard University researchers at the Broad Institute report that expansion in situ genome sequencing (ExIGS) linked nuclear abnormalities to hotspots of aberrant chromatin regulation, potentially ...

Shelley and colleagues simulated the motions of chromatin, the functional form of DNA inside the nucleus. Chromatin looks like beads on a string, with ball-like clusters of genetic material linked ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...

A multidisciplinary team of Indiana University researchers have discovered that the motion of chromatin, the material that DNA is made of, can help facilitate effective repair of DNA damage in the ...

Inside a nucleus, chromosomes jumble together like a game of Twister. This can bring regulatory elements, such as enhancers, from one chromosome into contact with genes from another chromosome, ...

There is more movement in our genome than we think. Almost half of the human genome consists of transposons—short DNA ...