Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, ...

A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a ...

However, the structure of chromatin also appears to serve a second, possibly more important role, in that it gives eukaryotic cells the capability to exert complex levels of control over gene ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

Scientists at St. Jude Children’s Research Hospital used a series of cryo-EM structures to visualize dynamics pivotal to ...

Varshavsky studied chromatin structure and wanted to develop new methods to detect the DNA-protein interplay in intact cells. Motivated to better understand chromatin structural organization, ...

During interphase, individual chromosomes are not visible, and the chromatin appears ... Because the centrosomes are located outside the nucleus in animal cells, the microtubules of the developing ...

Researchers analyzed gene expression and chromatin accessibility to detect populations with stem cell–like properties. Additional samples from donors between 16 and 22 weeks of gestation were used to ...

Using single-cell technologies, the researchers simultaneously analyzed the accessibility of genetic material through chromatin and the actual activity of relevant genes. Their findings reveal a ...