Inhibitors of apoptosis, ferroptosis and other cell death mechanisms had no effect on this process, suggesting disulfidptosis is a distinct pathway. The discovery of disulfidptosis offers a new ...

Cell Death Discovery is a multidisciplinary, international, online-only, open access journal, dedicated to publishing research at the intersection of medicine with biochemistry, pharmacology ...

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a ...

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause ...

Professor Stockwell will discuss the discovery of ferroptosis, a novel model of regulated but non-apoptotic cell death. He will describe how some tumors are sensitized to ferroptosis and may be ...

Prof De Strooper says the discovery that blocking the MEG3 molecule can hold off brain cell death could lead to a "whole new line of drugs development". However, this will take years of research.

Macronucleophagy helps control micronucleophagy to protect yeast cells during stress. Through extensive experiments with ...

Glaucoma is a progressive eye disorder characterized by fluid buildup inside the eye, causing ocular hypertension. By 2040, ...

During islet development, beta-cell death, rather than proliferation alone, regulates beta-cell mass and shapes the immune ...

Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model ...