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There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Familial hypercholesterolemia (FH) affects ∼1 in 250 individuals worldwide (prevalence∼400 per 100,000) (1), driven by PCSK9 gain-of-function and LDLR loss-of-functionmutations that elevate LDL-C and ...

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Journal: Policy Perspectives: The Journal of the Institute of Policy Studies Pakistan and Afghanistan are often bracketed as brother nations, having deep rooted historical links, traditional affinity, ...

Abstract Risk prediction models are an important part of assessing operative mortality and postoperative complication rates in current cardiac surgery practice. Furthermore, they guide clinical ...

Methods: We analyzed the incidence, distribution, and laboratory testing of human rabies in mainland China using statutory surveillance data from 2015-2021. Based on a literature review, the study ...

Mouse double minute 2 (MDM2) is an oncogenic E3 ligase that effectively degrades the tumor suppressor p53. In the past two decades, many MDM2 inhibitors that disrupt MDM2-p53 binding have been ...

The global landscape has witnessed profound transformations during the COVID-19 pandemic, which has concurrently catalysed notable advancements in scientific research while inflicting detrimental ...

Student evaluations of teaching (SET) are widely used in academic personnel decisions as a measure of teaching effectiveness. We show: SET are biased against female instructors by an amount that is ...

Recently, the monkeypox virus has begun to spread in many countries worldwide [1]. The genome sequence of the monkeypox virus variant responsible for the current outbreak has been reported, thus ...

The monkeypox outbreaks started in 2022 and became an unexpected public health emergency of international concern (PHEIC). The factors that drove this neglected zoonosis in Africa into a global focus ...