One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in ...

Researchers at Karolinska Institutet have identified small molecules capable of influencing a hard-to-target receptor family ...

The approval of the GLP-1 receptor agonist semaglutide for weight regulation in January 2023 ushered in a new era of obesity therapy. In recent months, however, drug regulatory authorities have also ...

The human P2X4 receptor plays an important role in chronic pain, inflammation and some types of cancer. Researchers at the ...

Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain, ...

When Christopher Klebanoff, MD, came to Memorial Sloan Kettering Cancer Center (MSK) from the National Cancer Institute in 2016, he was focused on a singular goal: bringing the promise of cellular ...

The sweet-taste receptor might be the first stop in a metabolic surveillance system for sugar. The receptor is also expressed in certain intestinal cells, where it may facilitate glucose absorption ...

Angiotensin II receptor blockers (ARBs) are drugs that treat certain conditions affecting the heart and blood vessels as well as a kidney condition resulting from diabetes. People generally tolerate ...

An Osaka Metropolitan University-led research team studied 5-HT3A receptor deletion in mice to assess behavioral persistence.

For the first time, researchers have determined how a human olfactory receptor captures an airborne scent molecule, the pivotal chemical event that triggers our sense of smell. Whether it evokes roses ...