Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. These ...

Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. By ...

Enzymes known as kinases play a critical role in cell growth, metabolism and signaling in a multitude of organisms across the tree of life—from algae to helminths to mammals. Now, scientists ...

The protein kinase CK2 is involved in a wide range of biological processes and cellular functions, including inflammatory responses and pathologies associated with inflammation.

Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. These ...

After more than 20 years, scientists have solved the full-length structure of a Janus Kinase Date: March 10, 2022 Source: Howard Hughes Medical Institute Summary: More than two decades of effort ...

These pseudo-kinases despite being catalytically inactive, perform numerous non-canonical kinase functions through their inactive ATP binding domain.

BRASSINOSTEROID-SIGNALING KINASE 1 phosphorylating CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE functions in drought tolerance in maize Lei Liu, Yang Xiang, Jingwei Yan, Pengcheng Di, Jing Li, Xiujuan ...

Through such analysis, investigators hope to better understand kinase function, identify new kinase inhibitors for cancer therapy, and screen candidates for side-effects on other pathways.

Xiuying Gao, Jia-Qi Zhang, Xiaojun Zhang, Jun Zhou, Zhisheng Jiang, Peng Huang, Zhengbin Tang, Yongmei Bao, Jinping Cheng, Haijuan Tang, Wenhua Zhang, Hongsheng Zhang, Ji Huang, Rice qGL3/OsPPKL1 ...