Background Pulmonary microvasculature alterations are implicated in emphysema pathogenesis, but the association between ...
Objective Anaesthesiology guidelines suggest that opioids worsen obstructive sleep apnoea (OSA) despite no randomised controlled trial evidence. We therefore conducted a randomised controlled trial to ...
Background We aimed to disentangle genetic and environmental causes in lung cancer while considering smoking status. Methods Four Nordic twin cohorts (43 512 monozygotic (MZ) and 71 895 same sex ...
Background Overexpression of the transforming growth factor β family signalling molecule smad2 in the airway epithelium provokes enhanced allergen-induced airway remodelling in mice, concomitant with ...
Background Life expectancy for people with cystic fibrosis (CF) varies considerably both within and between countries. The objective of this study was to compare survival among countries with ...
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Correspondence to Dr Mark Birrell, Respiratory Pharmacology, Faculty of Medicine, National Heart and Lung Institute, Imperial College London, Exhibition Road, London, SW7 2AZ, UK; ...
Structural and functional defects within the lungs of children with cystic fibrosis (CF) are detectable soon after birth and progress throughout preschool years often without overt clinical signs or ...
8 Department of Environmental Medicine and Public Health, Section of Occupational Medicine, University of Padova, Italy 9 Departments of Medicine, Oncology and Radiology, Section of Respiratory ...
Background: Oxidative stress is thought to have a major role in the pathogenesis of airway obstruction. A study was undertaken to determine whether subjects with low levels of antioxidants (serum ...
1 Department of General Practice, Division of Public Health, Academic Medical Center, University of Amsterdam, The Netherlands 2 Department of Clinical Epidemiology, Leiden University Medical Centre, ...