NAIROBI, Kenya — Police in Kenya clashed with demonstrators Monday during the latest anti-government protests, killing 10 people, according to the state-funded human rights commission. Authorities blocked major roads leading into the capital, Nairobi, and most businesses closed amid the strictest measures yet to contain the unrest.

Kenyan police opened fire on a crowd of advancing protesters in Nairobi on Monday, a Reuters reporter said, as scattered demonstrations broke out across the country to mark the 35th anniversary of pro-democracy rallies.

Kenya's security forces have blocked all major roads leading into central Nairobi, ahead of planned nationwide protests. Much of the city centre is deserted, with businesses shut and a heavy security presence on the streets. Some schools have advised students to stay at home.