Cryo-electron microscopy (cryo-EM) single particle analysis has rapidly become a cornerstone technique for high-resolution ...

Structure-based designs facilitate drug discovery, and cryogenic electron microscopy (cryo-EM) is an increasingly important tool to determine high-resolution structures of proteins and protein ...

Brussels, 13 November 2025 – Researchers at the VIB-VUB Center for Structural Biology have developed a new microfluidics-based workflow that enables high-resolution cryogenic electron microscopy (cryo ...

Cryo-electron microscopy (cryo-EM) has revolutionalized our understanding of the intricate molecular machinery that governs life. It has elucidated the three-dimensional (3D) structure of biological ...

What is Cryo-Electron Microscopy? Cryo-electron microscopy (cryo-EM) is a powerful technique used to determine the three-dimensional structure of biological macromolecules, such as proteins and ...

Using technologies like electron microscopy (EM) it is possible to capture molecular mechanisms in great detail, but not when these mechanisms are currently moving. The field of cryomicroscopy ...

RAB7A plays a central role in the final stages of autophagy, facilitating autophagosome-lysosome fusion, lysosome positioning, and cargo degradation. Its activation by guanine nucleotide exchange ...

The cryogenic electron microscopy (cryo-EM) field exploded in popularity during the 2010s' "resolution revolution." The 2017 Nobel Prize in Chemistry awarded Jacques Dubochet, Joachim Frank, and ...

A technology called cryo-electron microscopy enables scientists to see the atomic structure of biological molecules in high resolution. But to date, it has been ineffective for imaging small molecules ...