Neuronal degeneration leading to visual impairment or blindness remains a critical challenge in human health. Unlike humans, ...

These are the cells that make up the eye of a zebrafish only about a day after fertilization. The outermost layer contains skin cells (1) that will form the skin around the eye. In the middle layer ...

To expedite discovery of new drugs for these diseases, our group studies zebrafish retinal-degeneration models. Our lab is interested in the mechanisms that regulate neutrophil migration and ...

The study introduces new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment. This ...

The preclinical evaluation of drug-induced cardiotoxicity is an important stage in the drug development process; however, traditional methods for screening drug candidates, such as cardiomyocyte-based ...

Here, we are interested in determining whether the mouse retina retains latent regenerative potential akin to other vertebrates such as the zebrafish and whether we can genetically "awaken" that ...

A novel system that chases larval zebrafish around an arena with predator robots is enabling scientists to understand how these days-old fish quickly learn in the real world. A novel system ...

Zebrafish are unassuming and undemanding. Almost every child knows that – at least any child that has kept fish in an aquarium. Since the beginning of the 20th century, these fish have been one of the ...