Genome organization has a crucial role in controlling gene expression and overall genome function by spatially arranging chromatin and its regulatory elements within the nucleus 1,2,3,4. A fundamental ...
A long-standing question concerns the role of Z-DNA in transcription. Here we use a deep learning approach DeepZ that predicts Z-flipons based on DNA sequence, structural properties of nucleotides and ...
Under physiological conditions, most double-stranded nucleic acids adopt right-handed helical conformations such as B-DNA or A-RNA. However, under specific cellular stresses, nucleic acids can ...
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