The causative mutation is the substitution of valine for glutamic acid at the sixth position of the β globin chain (Glu6Val). Sickle cell hemoglobin (HbS) behaves like normal hemoglobin when ...

The latest round of CDC cuts could drastically impact those with sickle cell disease. Research teams could be eliminated and ...

In sickle-cell disease, a single nucleotide change within the haemoglobin beta subunit gene — swapping out the amino acid glutamate for valine — gives rise to defective molecules with ...

Ingram sequenced these two peptides and showed that the β chain of sickle cell hemoglobin had a valine residue at a position where normal hemoglobin had a glutamic acid residue 3. The atomic ...

NASHVILLE, Tenn. (WTVF) — One of Vanderbilt's latest studies has found a cure for sickle cell disease. Sickle cell is a blood disorder where the body creates mutated red blood cell proteins.