The causative mutation is the substitution of valine for glutamic acid at the sixth position of the β globin chain (Glu6Val). Sickle cell hemoglobin (HbS) behaves like normal hemoglobin when ...

Ingram sequenced these two peptides and showed that the β chain of sickle cell hemoglobin had a valine residue at a position where normal hemoglobin had a glutamic acid residue 3. The atomic ...

How do mutations happen, and how do they influence the future of a species? Molecules of sickle-cell hemoglobin stick to one another, forming rigid rods. These rods cause a person's red blood ...

The launching of the Sentara-Eastern Virginia Medical School Comprehensive Sickle Cell Program in October gave adults ...