For example, although the first baby with thalidomide-related birth defects was born before the drug was widely marketed, it was fully five years before the enormity of the tragedy was appreciated.
Upon its 'reinvention', thalidomide was quickly applied to 'microenvironment-dependent' diseases such as multiple myeloma, yet its role in the solid tumor spectrum has not been validated.
Thalidomide demonstrated superior efficacy in preventing the relapse of immunoglobulin G4–related disease (IgG4-RD) during a 12-month follow-up period in a placebo-controlled trial. The ...
Thalidomide was a widely used drug in the late ... After about 5 years on the market and 10,000 babies affected, the manufacturer Gruenthal withdrew it, leading to stern warnings from world ...