Researchers have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport neurotransmitters in the brain. The study could inform ...

Synaptic vesicles act as the brain’s chemical couriers, transporting neurotransmitters between cells. When a nerve impulse arrives, these vesicles fuse with the neuron’s membrane and release their ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...

For decades, neuroscientists have debated whether synaptic vesicles “kiss-and-run” or do an irreversible “full collapse” when releasing neurotransmitters. Now, a team in China has frozen that moment ...

Both presenilin-1 or the less-studied presenilin-2 can act as the catalytic subunit of γ-secretase, the enzyme responsible for churning out Aβ peptides. A new study, published November 29 in Nature ...

Extracellular vesicles (EVs), including exosomes, microvesicles, apoptotic bodies, and many other EV subtypes, have emerged ...

Max Delbrück Center for Molecular Medicine in the Helmholtz Association Researchers led by Uljana Kravčenko and her colleagues in the lab of Professor Misha Kudryashev, Group Leader of the In Situ ...