Good experiments start with good planning. The analysis of genetic and molecular information involves increasingly sophisticated tools and methodologies, many of which are advancing at a fast pace.

From outbreak investigations to clinical trials, the right study design can make or break public health research. Understanding the strengths, limitations, and applications of each approach helps ...

The development of oligonucleotide (ON) drugs such as antisense ONs and siRNAs has accelerated rapidly and is highly sought after, with increasing diversity in modalities and applications. The use of ...

Once you have determined your research question, the next step is to decide on a research design. As random assignment tends to be challenging in SoTL, most projects tend to fall into the ...

Clinical trials are well-controlled and designed experiments that aim to prove that an Investigational Medicinal Product (IMP) is effective. Clinical trial data is submitted to the national health ...

Aptiv Solutions, a biopharmaceutical and medical device development services company and pioneer in adaptive clinical trial design, simulation and execution, announces publication of a Tufts Center ...

Noninferiority clinical trials have become a major tool for the evaluation of drugs, devices, biologics, and other medical treatments. Treatment with placebo or with a no-treatment control in a study ...

As biomarker studies employ increasingly complex and expensive genomics and other correlative methods, it is increasingly important to rigorously design these studies and analyze the downstream ...