The apolipoprotein E4 (ApoE4) allele, the strongest known genetic risk factor for late-onset sporadic Alzheimer’s disease, puts women at higher risk for the disease than men, but how remains unclear.

In a recent study published in Jama Network, researchers investigated the impact of coronavirus disease 2019 (COVID-19) on biomarkers in the cerebrospinal fluid (CSF). Study: Viral Antigen and ...

Cerebrospinal fluid (CSF) and other biomarkers differ for individuals with Alzheimer disease and cognitively normal controls, with the estimated times of divergence varying from 18 to six years before ...

In the 1990s, a number of new chemotherapeutic agents such as the taxanes, vinorelbine, gemcitabine, and irinotecan were introduced into the management of advanced non-small-cell lung cancer (NSCLC).

Schizophrenia is a common, chronic and disabling neuropsychiatric disorder, affecting about 1% of the world's population. 1 It is a complex disorder that is likely to result from the interaction of ...

Clinicians have been eagerly awaiting results of the enormous Imaging Dementia–Evidence for Amyloid Scanning (IDEAS) study, which may determine whether amyloid scans will be covered by insurance.

NEW YORK, NY—Results from a pair of small, randomized studies suggest that using granulocyte-colony stimulating factor (G-CSF) to mobilize stem cells is safe and may improve long-term cardiac function ...

CRISPR/Cas9-Mediated GM-CSF knock-out (GM-CSF ko) CAR-T cells demonstrate reduced apoptosis and enhanced in vivo anti-tumor activity in preclinical models Phase 3 SHIELD study utilizing lenzilumab to ...

A phase 1 dose-escalation and expansion-cohort study of the oral CDK7 inhibitor XL102 as a single-agent and in combination therapy in patients (pts) with advanced solid tumors. This is an ASCO Meeting ...