Chimeric antigen receptor T cell (CAR-T) therapy is considered one of the landmark achievements of modern medicine. The therapy involves harvesting a patient’s own immune cells, genetically ...

This article and associated images are based on a poster originally authored by Marisa Amato and presented at ELRIG Drug Discovery 2025 in affiliation with Singleron Biotechnologies GmbH. This poster ...

D&D‑seq uses base editing to record DNA–protein interactions in single cells, enabling multiomics mapping of transcription ...

Researchers increasingly turn to single-cell sequencing to answer a range of biological questions, with published single-cell data increasing year over year. As its popularity rises, so does the need ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...

A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and other ...

Scientists have created the most detailed cell map to date showing how genetic variation influences inflammatory bowel ...

Persistent viral infections pose a unique challenge to the immune system. Prolonged antigen exposure drives T cells into a state of exhaustion — a ...

A study published in Nature Aging has detailed this cellular transformation. The findings demonstrate that immunosenescence, ...