Chloroplast ribosomes, which originated from cyanobacteria, comprise a large subunit (50S) and a small subunit (30S) containing ribosomal RNAs (rRNAs) and various ribosomal proteins. Genes for many ...

The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the entry ...

Life runs on ribosomes. Every cell on earth needs ribosomes to translate genetic information into all the proteins needed for the organism to function—and to in turn make more ribosomes. But ...

At the end of the 1970s, Ada Yonath decided she was going to generate crystal structures of the ribosome using x-ray crystallography to establish the exact location of every atom -- considered an ...

One year later, in these Hot Papers, Ramakrishnan's group described the complete structure of the 30S subunit at 3 Angstrom resolution, both isolated and complexed with antibiotics. This information ...

In the 1940s, scientists at the recently established National Cancer Institute were trying to breed mice that could inform our understanding of cancer, either because they predictably developed ...

In a recent study in Nature, researchers identified and characterized a broad-spectrum antibiotic, lariocidin (LAR). The antibiotic inhibits bacterial growth by altering protein synthesis in ribosomes ...