Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

Researchers report a drug discovery strategy using tailor-made cyclic peptides to target β-arrestins, key regulators of ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug ...

Here’s what you’ll learn when you read this story: When cells are about to die, they send signals that trigger proteins which are supposed to destroy them, but it doesn’t always happen that way. Some ...

Researchers have created a method called optovolution that uses light to guide the evolution of proteins with dynamic behaviors. By engineering yeast cells so their survival depended on proteins ...

A research team led by Sahand Jamal Rahi at EPFL’s Laboratory of the Physics of Biological Systems has introduced a new ...

In people destined to get Alzheimer's in their mid-40s, one protein can delay the onset of the disease by about 20 years.

EPFL researchers have developed a light-based method that can produce proteins that switch states, respond to signals, and even compute, using light and the cell cycle.

A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...

Large protein machines in the body carry out many of the cell's most essential tasks, from energy production to the ...

For decades, researchers have used that green fluorescent protein and similar molecules to light up the field of biology, tracking what’s happening inside cells. Now these ubiquitous tools are ...