For years, biomolecular condensates were thought to be simple, liquid-like droplets with little internal organization. New ...

A metabolic enzyme studied for over seven decades has a hidden second function—it can unwind RNA and promote cell cycle progression, an additional function beyond its role in energy production, ...

AHNAK, a colossal scaffolding protein of approximately 700 kDa, has emerged as a critical player in various cellular functions, most notably in the regulation of cell architecture, signalling and ...

A newly identified role for the neuronal MPS shows it controls nutrient uptake by acting as a gatekeeper. Its disruption ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics.

Researchers have created nanoparticles that can remove disease-driving proteins while also delivering a chemotherapeutic or ...

A protein long studied for its role in amyotrophic lateral sclerosis and frontotemporal dementia now appears to serve a ...

Researchers have created a method called optovolution that uses light to guide the evolution of proteins with dynamic behaviors. By engineering yeast cells so their survival depended on proteins ...

In the evolutionary history of life, the ability of a cell to separate its inner world from the external environment was an ...

Many biological functions are regulated by the switching on and off of mechanisms triggered by the matching of a keyhole ...

Researchers found microglia influence reproductive hormone signaling through the RANK protein. The discovery links immune cells to puberty control and infertility, and may improve diagnosis and ...